How To Rank Molecules By Pka Acid Strength

In this video, I explain the five factors that influence acid strength of protons in different molecules. I work through several examples illustrating all five factors and how this is used to ranked the overall acid strength. Questions begin at 12:01

1) ClCH2COOH vs FCH2COOH (Inductive effect) 12:01
2) CH3CH2NH2 vs CH3CH2OH (Electronegativity) 15:40
3) CH3CH2CH3 vs CH3CH=CH2 (Hybridization) 17:45
4) CH3CH2OH vs CH3CH2SH (Atomic size) 19:33
5) CH3COOH vs CH3CH2OH (Resonance stabilization of the conjugate base) 21:49
6) CH3CH=CH2 vs CH3CCH (Hybridization) 24:07
7) HBr vs HI (Atomic size) 25:28
8) H2SO4 vs HNO3 (Resonance stabilization of the conjugate base) 26:48
9) Ranking in order of decreasing acid strength or increasing pKa 30:20
H2SO4, CH3COOH, FCH2COOH, CH3CCH, CH3CH2OH, CH3CH2SH